Single Nucleotide Polymorphisms (SNPs) in Non‐Small Cell Lung Cancer (NSCLC) Patients
نویسندگان
چکیده
منابع مشابه
Single nucleotide polymorphisms as susceptibility, prognostic, and therapeutic markers of nonsmall cell lung cancer.
Lung cancer is a major public health problem throughout the world. Among the most frequent cancer types (prostate, breast, colorectal, stomach, lung), lung cancer is the leading cause of cancer-related deaths worldwide. Among the two major subtypes of small cell lung cancer and nonsmall cell lung cancer (NSCLC), 85% of tumors belong to the NSCLC histological types. Small cell lung cancer is ass...
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New therapeutic approaches are being developed based on the findings that several genetic abnormalities underlying non-small-cell lung cancer (NSCLC) could influence chemosensitivity. In this study, we assessed whether polymorphisms in genes of nucleotide excision repair (NER) pathway, including ERCC5, ERCC6, MMS19L, CCNH, XPC, RRM1, can affect the tolerability of platinum-based chemotherapy in...
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Lymphedema is abnormal accumulation of interstitial fluid, due to Introduction inefficient uptake and reduced flow, leading to swelling and disability, mostly in the extremities. Hereditary lymphedema usually occurs as an autosomal dominant trait with allelic heterogeneity. We identified single Methods: nucleotide polymorphisms (SNPs) in the FOXC2 gene using dbSNP, analyzed their effect on the ...
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ژورنال
عنوان ژورنال: The Oncologist
سال: 2012
ISSN: 1083-7159,1549-490X
DOI: 10.1634/theoncologist.2012-0205